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Product Name: Seta-555-DBCO

Product Number:
K8-3345
Target Group:
N3
Excitation Light Sources:
Medium 1:
PB 7.4
λAb max. [nm]:
555
ε [M–1 cm–1]:
155000
λEm max. [nm]:
570
QY [%]:
7
Specs Sheet:
Download

Description

  • Highly hydrophilic click chemistry reagent containing one dibenzocyclo-octyne (DBCO) group for strain-mediated cycloaddition reactions with azides. It features the same excitation and emission wavelengths as Cy3™ and Alexa Fluor™ 555 and can therefore be used with these filter sets. It combines high photostability and brightness.

 

Applications

  • Strain-mediated click chemistry reactions with azide-modified reagents and biomolecules.

 

Advantages

  • The dye is excitable with green and yellow light sources and perfectly suited for excitation with 532-nm and 550-nm LEDs and diode lasers
  • Good aqueous solubility: this label does not alter the solubility of the protein conjugate
  • Low molecular weight: Seta-555-DBCO does not add substantial mass to the conjugates
  • Photostability: Higher photostability as compared to Alexa Fluor™ 555 or Cy3
  • Ideal for non-radioactive labeling of azide-modified molecules (drugs, proteins, oligos, and DNA)